Progressive Protein Concentration Sytems µTFF
The assignment for our team was to create a concept for a chamber for progressive protein processing by means of tangential flow filtration (TFF).
It was also to be equipped with pressure sensors for differential measurement of pressure. In addition it should also be provided with an optical cuvette to determine the protein concentration by means of absorption measurement.
The core idea of our concept for absorption measurement of progressive protein concentration was a set of optics adapted to a capillary system.
The design of the chamber was optimized with respect to laminar streamlines and integration of pressure sensors.